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Normal and PDAC parenchymal cells. Diagram representing the parenchymal cellular components of the normal exocrine pancreas, PanIN pre-malignant lesions and PDAC. Histological features of each includes acini (1), ducts (2), atypic cells in panIN lesions (3), PDAC cells undergoing epithelial-to-mesenchymal transition (4), invasive PDAC migrating as individual cells.
