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. 2020 Sep 25;9(10):643. doi: 10.3390/antibiotics9100643

Table 3.

Rank order (decreasing) of the incidence of male lung cancer (10 countries) compared to the rank order (decreasing) of antibiotics with suspected “promoter” effect and the increasing (reverse) rank order of the suspected “inhibitor” effect of antibiotics. Of the first ten countries with the highest incidence rate of male lung cancer, nine countries can be found among the highest consumption figures of “promoter” antibiotics (exception: Poland). Seven countries with the lowest consumption figures of “inhibitor” antibiotics, are among the first high incidence rate of male lung cancer (exception: Hungary, Lithuania, Estonia)

Incidence of Lung Cancer (Male) in Decreasing Rank Order Rank Order (Decreasing) of Antibiotics with Possible “Promoting” Effect on the Development of Lung Cancer
Countries New Cases/100,000 Inhabitants 2018 Countries J01CA + J01CR (%) Countries J01D (%) Countries J01F (%)
Hungary 111.6 Spain 49.07 Greece 24.59 Greece 27.75
Greece 99 Italy 41.99 Malta 23.24 Austria 26.71
Slovakia 79.7 France 41.6 Cyprus 21.53 Slovakia 22.06
Poland 78.5 Romania 41.32 Romania 19.03 Italy 21.78
Belgium 78.1 Lithuania 40.22 Luxembourg 18.62 Hungary 20.77
Latvia 77.6 Portugal 39.57 Croatia 17.72 Malta 20.58
Lithuania 77 Belgium 38.31 Slovakia 16.87 Czech Rep 19.89
Estonia 76.3 Latvia 37.31 Germany 16.82 Estonia 19.39
Croatia 75.6 Croatia 36.28 Bulgaria 14.71 Slovenia 19.39
France 74.2 Cyprus 34.93 Hungary 14.28 Germany 19.02
Incidence of Lung Cancer (Male) in Decreasing Rank Order Rank Order (Increasing) of Antibiotics with Possible “Inhibitor” Effect on the Development of Lung Cancer
Countries New cases/100,000 inhabitants 2018 Countries J01CE + J01CF (%) Countries J01A (%)
Hungary 111.6 Italy 0.12 Ireland 2.8
Greece 99 Cyprus 0.43 Slovenia 4.06
Slovakia 79.7 Malta 0.66 Romania 4.1
Poland 78.5 Latvia 0.95 Portugal 5.74
Belgium 78.1 Luxembourg 1.29 Spain 5.79
Latvia 77.6 Belgium 1.6 Malta 6.53
Lithuania 77 Greece 1.63 Croatia 7.9
Estonia 76.3 Spain 1.86 Greece 8.26
Croatia 75.6 France 2.17 Slovakia 8.56
France 74.2 Poland 2.32 Austria 9.21

J01CA—broad-spectrum, beta-lactamase sensitive penicillin; J01R—broad-spectrum penicillin with beta-lactamase inhibitors; J01D—cephalosporin; J01F—macrolide; J01CE—narrow-spectrum, beta-lactamase-sensitive penicillin; J01CF—narrow-spectrum, beta-lactamase-resistant penicillin; J01A—tetracycline.