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. 2020 Sep 29;7(10):63. doi: 10.3390/medicines7100063

Table 3.

Poly-methylated flavonoids from Stachys spp.

Species Plant Parts Compound Ref
Subgenus Stachys
Section Ambleia
S. aegyptiaca Pers. Aerial parts Xanthomicrol (69), Sideritiflavone (70),
5-Hydroxy-6,7,8,3′,4′-pentamethoxyflavone (75), 5,4′-Dihydroxy - 6,7,8,3′-tetramethoxyflavone (76), 5,3′,4′-Trihydroxy-3,6,7,8-tetramethoxyflavone (82), Calycopterin (83), Chrysosplenetin (84), 5-Hydroxy-3,6,7,8,4′- pentamethoxyflavone (88), 5,4′-Dihydroxy -3,6,7,8,3′- pentamethoxyflavone (89)
[68]
Aerial parts 5,7,3′-Trihydroxy-6,4′-dimethoxyflavone (67), 5,7,3′-Trihydroxy-6,8,4′-trimethoxyflavone (68) [70]
Aerial parts Xanthomicrol (69), Eupatilin-7-methyl ether (73), Calycopterin (83), 5-Hydroxy-3,6,7,4′-tetramethoxy flavone (85), 5,8-Dihydroxy-3,6,7,4′-tetramethoxy flavone (86), 5-Hydroxy-auranetin (88), 4′-Hydroxy-3,5,7,3′- tetramethoxy flavone (90) [106]
S. schtschegleevii Sosn. ex Grossh. Stems Cirsimaritin (66), Xanthomicrol (69) [74]
Section Aucheriana
S. glutinosa L. Xanthomicrol (69), Sideritiflavone (70), 8-Methoxycirsilineol (71), Eupatilin (72a) [107]
Section Candida
S. candida Bory & Chaubard Aerial parts Xanthomicrol (69), Calycopterin (83) [77,78]
S. chrysantha Boiss. and Heldr. Aerial parts Xanthomicrol (69), Calycopterin (83) [77]
Section Swainsoniana
S. swainsonii Benth. subsp. swainsonii Aerial parts Eupatorin (72), Penduletin (81), 5-Hydroxyauranetin (88) [102]
S. swainsonii subsp. argolica (Boiss.) Phitos and Damboldt Aerial parts Xanthomicrol (69), Eupatorin (72),
Salvigenin (74)
[102]
S. swainsonii subsp. melangavica D. Persson Aerial parts Eupatorin (72), 5-Hydroxyauranetin (88) [102]
S. swainsonii subsp. scyronica (Boiss.) Phitos and Damboldt Aerial parts Eupatorin (72), Penduletin (81), 5-Hydroxyauranetin (88) [102]
S. ionica Halácsy Aerial parts Xanthomicrol (69), Salvigenin (74), Chrysosplenetin (84), 5-Hydroxy-3,6,7,4′-tetramethoxyflavone (85), Casticin (87) [20]
S. lavandulifolia Vahl. Aerial parts Velutin (Luteolin 7,3′-dimethyl ether) (65), Viscosine (5,7,4′-trihydroxy-3,6-dimethoxyflavone (78), Kumatakenin (Kaempferol 3,7-dimethyl ether) (79), Pachypodol (Quercetin 3,7,3′-trimethyl ether) (80), Penduletin (81), Chrysosplenetin (84), [13]
Subgenus Betonica
Section Betonica
S. officinalis (L.) Trevis = (Betonica officinalis L.) 5,4′-Dyhydroxy-7,3′,5′-trimethoxyflavone (77) [20]