Table 3.

Serum metabolites with significant concentration changes at least during one phase of the project.

All Together	Phase I vs. Phase II	FC	Phase II vs. Phase III	FC	Phase I vs. Phase III	FC
proline	0.018	0.32	0.886	0.02	0.014	0.34
pyruvate	0.078	0.41	0.292	0.25	0.0006	0.65
dimethylglycine	0.046	−0.33	0.755	0.20	0.656	−0.13
phenylalanine	0.018	0.23	0.806	0.001	0.0006	0.23
B + BL Group	Phase I vs. Phase II	FC	Phase II vs. Phase III	FC	Phase I vs. Phase III	FC
pyruvate	0.209	0.46	0.762	0.31	0.033	0.77
phenylalanine	0.209	0.28	0.711	−0.003	0.038	0.28

p-values, obtained using FDR correction method and log₂ (fold change) (FC) values are reported. Positive FC: increment; negative FC: decrement (in the second group of each comparison with respect to the first).