Table 4.
Content of integrins in hLMVEC, MCF-7 and MDA-MB-231 cell lines.
| Integrin | hLMVEC [Mean ± SD] | MCF-7 [Mean ± SD] |
MDA-MB-231 [Mean ± SD] |
|---|---|---|---|
| β1 | 0.853 ± 0.133 | 0.250 ± 0.180 | 0.950 ± 0.499 |
| β3 | 0.100 ± 0.000 | not detected | not detected |
| β4 | 0.050 ± 0.036 | 0.110 ± 0.000 | 0.347 ± 0.119 |
| β5 | 0.050 ± 0.000 | 0.050 ± 0.000 | 0.050 ± 0.000 |
| α2 | 0.430 ± 0.000 | 0.180 ± 0.000 | 0.407 ± 0.151 |
| α3 | 0.157 ± 0.075 | not detected | 0.520 ± 0.115 |
| α5 | 0.477 ± 0.064 | not detected | 0.080 ± 0.000 |
| α6 | 0.183 ± 0.100 | not detected | 0.270 ± 0.200 |
| αV | 0.387 ± 0.050 | 0.040 ± 0.000 | 0.103 ± 0.060 |
Semi-quantitative data (emPAI) for integrins detected in lysates from human lung microvascular endothelial cells (hLMVEC) and breast cancer MCF-7 and MDA-MB-231 cell lines. Data represent the means ± SD from three consecutive passages. emPAI was calculated based on the number of observed peptides per proteins normalized by the theoretical number of peptides subtracted from LC-MS/MS data using MascotTM (Matrix Sciences, London, UK).