Figure 4.
Effect of coating SCC on gene expression of cell migration and extracellular matrix (ECM) markers in HDFa. HDFa were cultured on TSC- or SCC-coated dishes for indicated times. The RNA was extracted and qRT-PCR analysis was carried out to determine the gene expressions of (A) migration markers (N-cadherin, Snail, and MMP 1) at 6 h and (B) ECM markers (collagen Iα1, collagen IIIα1, elastin, and hyaluronan synthases 2) at day 2. Mean values within each column with different labels (a–e) are significantly different (p < 0.05) according to one-way ANOVA analysis of variance and Duncan’s multiple range test.
