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. 2020 Oct 11;18(10):511. doi: 10.3390/md18100511

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of SCC on promoting wound healing in C57BL/6J mice. SCC or TSC application on skin wound was described as Materials and Methods. Wound closure is expressed as a percentage of initial wound area at day 0. (A) Representative photographs of the wounds at days 0, 2, 4, 6, 8, and 10 after creating skin excisional wounds. (B) Quantitative analysis of SCC or TSC improved the rate of wound closure. Mean values within each column with different labels (a–c) are significantly different (p < 0.05) according to one-way ANOVA analysis of variance and Duncan’s multiple range test. (C) Histopathology of skin wounds at day 5 and day 10 after surgery. S: Scab; G: Granulation; E: Epidermis; A: Adipocyte; H: Hair follicle; B: Blood vessel; N: Necrosis; M: Inflammatory cells.