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. 2020 Oct 9;10(10):1836. doi: 10.3390/ani10101836

Table 3.

Gene Ontology, KEGG and Reactome pathways where the candidate genes are significantly enriched (p < 0.05).

Traits a Term ID Term Name Genes p-Value
BT GO:0006869 lipid transport PRELID1 0.010233961
GO:0010876 lipid localization PRELID1 0.014172362
GO:0005319 lipid transporter activity PRELID1 0.019846208
GO:0006629 lipid metabolic process FGFR4 0.025006995
GO:0008289 lipid binding COMMD1, PFN3 0.047311441
GO:0008610 lipid biosynthetic process FGFR4 0.035303187
KEGG:04015 Rap1 signaling pathway RGS14 0.047961872
CW GO:0001558 regulation of cell growth SGK3 0.044446017
GO:0007173 epidermal growth factor receptor signaling pathway FAM83A 0.039752933
GO:0016049 cell growth POU4F3 0.035059849
GO:0035264 multicellular organism growth PLAG1 0.030366765
GO:0035265 organ growth PLAG1, CGA 0.025673681
GO:0040007 growth PLAG1, POU4F3, CGA, SGK3 0.020980597
GO:0048589 developmental growth PLAG1, POU4F3, CGA 0.016287514
GO:0060560 developmental growth involved in morphogenesis POU4F3 0.01159443
GO:0005515 protein binding ARFGEF1, ATAD2, LYN, MYBL1, RB1CC1, AKIRIN2, CRH, CGA, NPBWR1, PENK, PPP1R42, RGS20, TCERG1, ZHX1, ZHX2 0.006901346
KEGG:04080 Neuroactive ligand-receptor interaction CGA, HTR1E, NPBWR1, OPRK1, PENK, CRH 0.039862933
EMA GO:0006629 lipid metabolic process LYN, SDR16C5 0.049805624
GO:0019216 regulation of lipid metabolic process LYN 0.042803519
GO:0033993 response to lipid DDX5 0.043747312
GO:0008289 lipid binding TEX2 0.049508111
KEGG:04514 Cell adhesion molecules LOC100140873, PECAM1 0.04067771
REAC:R-BTA-210990 PECAM1 interactions LYN, PECAM1 0.049805624
MS GO:0006629 lipid metabolic process CREBL2 0.01889403
GO:0006869 lipid transport APOLD1, MSR1 0.041826385
GO:0008610 lipid biosynthetic process CREBL2 0.021157549
GO:0010876 lipid localization APOLD1 0.016791777
GO:0019915 lipid storage MSR1 0.025742261
GO:0045444 fat cell differentiation CREBL2 0.019486141
GO:0008289 lipid transport APOLD1 0.017945142
GO:0071814 protein-lipid complex binding MSR1 0.016404143
KEGG:04010 MAPK signaling pathway DUSP16, FGF20 0.014863145
REAC:R-BTA-5673001 RAF/MAP kinase cascade DUSP16, FGF20, GRIN2B 0.016791777
YW GO:0001558 regulation of cell growth ADAM10, SGK3 0.046130564
GO:0016049 cell growth ADAM10 0.043928692
GO:0035264 multicellular organism growth PLAG1 0.04172682
GO:0035265 organ growth PLAG1 0.039524949
GO:0040007 growth ADAM10, PLAG1, SGK3 0.037323077
GO:0040008 regulation of growth ADAM10, SGK3, MYO1E 0.035121205
GO:0048589 developmental growth PLAG1 0.032919333
GO:0070848 response to growth factor IBSP, RNF111 0.030717462
GO:0071363 cellular response to growth factor stimulus RNF111 0.02851559
GO:0005515 protein binding ADAM10, ARFGEF1, LYN, MYBL1, PPARGC1A, RB1CC1, CRH, MEPE, NPBWR1, PKD2, PENK, PPP1R24, RGS20, SPP1 0.026313718
GO:0140096 catalytic activity, acting on a protein ADAM10, CCNB2, COPS5, CPA6, GGH, HERC3, HERC5, HERC6, LYN, MOS, PCMTD1, PPM1K, RNF111, RNF139, SGK3, VCPIP1, NSMCE2 0.048130564

a BT, Backfat Thickness; CW, Carcass Weight; EMA, Eye Muscle Area; MS, Marbling Score; YW, Yearling Weight.