Skip to main content
. 2020 Oct 6;12(10):2868. doi: 10.3390/cancers12102868

Figure 1.

Figure 1

WT vs G-CSFR−/− BMM express similar macrophage markers, but altered cytokine and NOS2 expression as shown by (A) Flow cytometry analysis for CD11b, MHC-II, CD115 and GR-1 and (B) Real-Time PCR analysis showing in the absence G-CSFR, there is downregulation of IL-10 and ARG-1 and upregulation of IL-12 and NOS2 mRNA levels compared to WT. (C) Results for ARG-1 and NOS2 were confirmed by flow cytometry showing increased NOS2 and reduced ARG-1 in LPS + IFNγ activated G-CSFR−/− BMMs compared to WT. n = 6, * p < 0.05.