AKT	Protein kinase B
APC	Antigen presenting cell
APE1	Apurinic/apyrimidinic endonuclease 1
BAD	BCL2 associated agonist of cell death
BRAF	v-Raf murine sarcoma viral oncogene homolog B
CAFs	Cancer-associated fibroblasts
CAR-T	Chimeric antigen receptor T-cells
CCL2	C-C Motif Chemokine Ligand 2
CCL-22	C-C motif chemokine 22
CD	Cluster differentiation
CRAF	v-raf1 murine leukemia viral oncogene homolog 1
CTL	Cytotoxic lymphocytes
CTLA-4	cytotoxic T-lymphocyte-associated protein 4
CXCL-2	CXC chemokine ligand 2
CXCL5	CXC motif chemokine 5
DCs	Dendritic cells
DNAM-1	DNAX accessory molecule-1
ECM	Extracellular matrix
EMT	Epithelial mesenchymal transition
ErbB3	V-erb-b2 avian erythroblastic leukemia viral oncogene homolog3
ERK	Extracellular signal-regulated kinase
FAK	Focal adhesion kinase
FAP	Fibroblast activation protein
FcγR	Fragment crystallizable-gamma receptor
FDA	Food and Drug Administration
FGF 2-19	Fibroblast growth factor 2-19
FGFR-3	Fibroblast growth factor receptor 3
FSP1	Fibroblast specific protein 1
GSK3β	Glycogen synthase kinase 3 beta
Gp	Glycoprotein
HER3	V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
HGF	Hepatocyte growth factor
ICIs	Immune checkpoint inhibitors
IDO	Indoleamine-2,3-dioxygenase
Ig	Immunoglobulin
IGF-1	Insulin-like growth factor 1
IGF-1R	Insulin-like growth factor receptor 1
IL	Interleukin
ITIM	Immunoreceptor tyrosine-based inhibition motif
KIT	v-kit Hardy–Zuckerman 4 feline sarcoma viral oncogene homolog
LIPA	Lysosomal acid lipase A
MAPK	Mitogen-activated protein kinase
MCL-1	Myeloid leukemia cell protein 1
MCH-I	Major histocompatibility complex 1
MDSCs	Myeloid-derived suppressor cells
MEK	Mitogen-activated protein kinase kinase
MET	Mesenchymal epithelial transition receptor
MHC	Major histocompatibility complex
miRNA	microRNA
MITF	Microphthalmia-associated transcription factor
MMPs	Matrix metalloproteinases
NFkB	Nuclear factor kappa-light-chain-enhancer of activated B cells
NGS	Next-generation sequencing
NK	Natural killer
NKG2D	Natural killer group 2D
NRAS	Neuroblastoma RAS viral oncogene homolog
NRG-1	Neuregulin 1
ORR	Objective response rate
OS	Overall survival
PBMC	Peripheral blood mononuclear cells
PD-1	Programmed cell death protein 1
PDGFR	Platelet-derived growth factor receptor
PDL-1/2	Programmed death ligands 1/2
PI3K	Phosphatidyl Inositol 3-kinase
PFS	Progression-free survival
PTEN	Phosphatase and tensin homolog on chromosome 10
ROS	Reactive oxygen species
RTK	Tyrosine kinase receptor
sFRP2	Secreted frizzled-related protein 2
STAT	Signal transducer and activator of transcription
SRC	V-src sarcoma (Schmidt–Ruppin A-2) viral oncogene homolog avian
TAB	Tumor-associated B cells
TAMs	Tumor-associated macrophages
TCF7	Transcription factor 7
TGF-β	Transforming growth factor β
TIGIT	T cell Ig and ITIM domain
TIL	Tumor-infiltrating lymphocytes
Tim3	Immunoglobulin and mucin domain-containing molecule 3
TME	Tumor microenvironment
TNFα	Tumor necrosis factor α
TRAF6	Tumor necrosis factor receptor-associated factor 6
Tregs	Regulatory T cells
VEGF	Vascular endothelial growth factor
VISTA	V-domain Ig suppressor of T cell activation
Wnt	wingless type MMTV integration site family member
α-SMA	α smooth muscle actin