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Caseating granulomas in humans and mice. Contrary to widespread belief, mice are able to develop several types of caseating granulomas each of which resembles a type of human lesion. This requires that one duplicate the conditions that occur in humans when the lesions develop rather than the route and dose of infection [135] (H&E stain Left and center) (Connective tissue stain, Right, showing a fibrous capsule).
