Figure 2.

In vivo toxicity assessment of the compound 18. Two doses (20 and 50 mg/kg) were administered intraperitoneally (IP) in CD-1 mice (n = 5 for each dose). Blood samples were collected 24 h later and tested by 14 parameters for organ functions. The red and green lines indicate the normal ranges for the assays. U, untreated animals; S, animals injected with saline (vehicle control).