Table 2.

Overview of ubiquitin-related genes modulated in HNSCC and have a potential role in NFκB activity.

Gene	Genomic Status	Known Role in NFκB in HNSCC?
BIRC2/3	Amplification, mRNA upregulation	√
TRAF3	Deletion, mutation	√
OTUB1	mRNA upregulation	X
CYLD	Mutation	√
FBXW7 α	Mutation	X
CUL3	Mutation	X
KEAP1	Mutation	X