Table 3.

Performance of ARFI for detecting different stages of liver fibrosis in NAFLD patients.

Fibrosis Stage	≥F2			≥F3			≥F4
Study	Cut-Off (m/s)	AUROC	Se/Sp (%)	Cut-Off (m/s)	AUROC	Se/Sp (%)	Cut-Off (m/s)	AUROC	Se/Sp (%)
Lin et al. (n = 1147 1) [105]	1.3	0.89	85/83	2.06	0.94	90/90	1.89	0.94	90/95
Jiang et al. (n = 982 1) [84]	N/S	0.86	70/84	N/S	0.94	89/88	N/S	0.95	89/91
Lee et al. (n = 94) [85]	1.35	0.657	46.2/93.2	1.43	0.873	70/93.7	1.50	0.92	75/90.7
Cassinotto et al. (n = 291) [87]	0.95 1.32	0.77	90/36 56/91	1.15 1.53	0.84	90/63 59/90	1.3 2.04	0.84	90/67 44/90
Cui et al.(n = 125) [110]	1.34	0.848	81.8/78.3	1.34	0.896	95.2/74	2.48	0.862	77.8/93.1
Fierbinteanu et al. (n = 64) [101]	1.165	0.944	84.8/90.3	1.48	0.982	86.4/95.2	1.635	0.984	91.7/92.3
Cassinotto et al. (n = 321) [111]	1.38	0.81	71/78	1.57	0.85	75/80	1.61	0.88	74/78
Friedrich-Rust et al. 2 (n = 57) [68]	N/S	0.66	N/S	N/S	0.71	N/S	N/S	0.74	N/S
Osaki et al. (n = 23 3) [103]	1.79 ± 0.78	N/S	N/S	2.20 ± 0.74	N/S	N/S	2.90 ± 1.01	N/S	N/S
Yoneda et al. (n = 54) [112]	N/S			1.77	0.93	100/91	1.90	0.937	100/96

¹ meta-analysis, ² ARFI measurement for the right lobe, ³ NASH patients.