Table 1.
Steroid regulatory molecules affecting CcO.
| Inhibition of CcO Oxidase Activity |
Inhibition of CcO Peroxidase Activity | Spectral Response Induced in Oxidized CcO | ||
|---|---|---|---|---|
| DM Influence | Ki, mM (DM→0) | |||
| Estradiol | competes 1:1 | 0.37 | no | red shift of a33+; ε = 10 mM−1⋅cm−1 |
| Testosterone | competes 1:1; increases maximal level of inhibition |
0.08 | no | no |
| Dehydroepiandrosterone (DHEA) | competes 1:1 | 0.11 | no | no data |
| Progesterone | competes 1:1 | 0.12 | no | no data |
|
Cholecalciferol
(vitamine D3) |
competes 1:1 | 0.009 | yes (Ki ~0.2 mM) |
red shift of a33+; ε = 25 mM−1⋅cm−1 |
|
Ergocalciferol
(vitamine D2) |
competes 1:1 | 0.02 | no data | no data |