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. 2020 Sep 28;12(10):2780. doi: 10.3390/cancers12102780

Figure 4.

Figure 4

Therapeutic strategies targeting the metabolism of CSCs. If CSCs depend on a particular metabolism, a single metabolic inhibitor can effectively eliminate the tumor. When multiple CSCs with distinct metabolic phenotypes are present in the same tumor, it is necessary to simultaneously inhibit multiple metabolic pathways to eliminate the tumor.