Table 1.
Potential targetable biomarkers for theranosis (TASC-T) scoring criteria.
No. | Parameter | Score |
---|---|---|
1 | Extracellular or membrane localisation of biomarker | 5 |
2 | >20% positivity in tumor tissue | 4 |
3 | Tumor to normal tissue ratio >10 | 3 |
4 | Percentage positivity or upregulation in tumor tissue | |
>90% | 6 | |
70–90% | 5 | |
50–69% | 3 | |
<49% | 0 | |
5 | Previous application to imaging | |
Preclinical | 1 | |
Clinical | 2 | |
6 | Ligand in human trials | 1 |
Total | 22 |