Table 2.
Summary of mechanisms underlying transcriptional regulation and latency of deltaretroviruses.
No. | Regulatory mechanism |
---|---|
1 | Epigenetic mechanisms |
2 | Transcription factors acting as activators |
3 | Tissue-specific expression of the proviral genome |
4 | Viral transactivator Tax is critical for viral infectivity and pathogenesis |
5 | Transcription factors acting as repressors |
6 | Glucocorticoid hormones can modulate the induction of BLV expression and pathology |
7 | LTR sequence variation plays an important role in retroviral replication and modulation of viral latency |
8 | Host and viral ncRNA play important role in regulation of retrovirus transcription |