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. 2020 Sep 30;12(10):628. doi: 10.3390/toxins12100628

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Phase II biotransformation of deoxynivalenol (DON): (A) Deepoxy-deoxynivalenol (DOM-1) by deepoxidation; (B) DON-3-sulfate, (D) DON-10-sulfate, (G) DON-3-glucoside sulfonate and (H) DOM-1-10-sulfonate by sulfation; (C) DON-glutathiones by conjugation with glutathione; (E) DON-3-glucuronide, DON-7-glucuronide, DON-8-glucuronide, and DON-15-glucuronide by conjugation with glucuronic acid; and (F) DON-3-glucoside by conjugation with glucose. GSTs: Glutathione S-transferases; UGTs: Uridine 5′-diphospho-glucuronosyltransferases [102].