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. 2020 Sep 30;12(10):628. doi: 10.3390/toxins12100628

Figure 5.

Figure 5

Metabolic pathway of T-2 toxin (T-2): (A) HT-2 toxin (HT-2), (B) Neosolaniol (NEO), (C) 4-deacetyl-NEO, (D) 15-deacetyl-NEO, (E) T-2 triol and (F) T-2 tetraol by hydrolysis; (G) 3′-hydroxy-T-2, (H) 3′-hydroxy-HT-2 and (I) 3′-hydroxy-T-2 triol by hydroxylation; (J) Deepoxy 3′-hydroxy-T-2 triol, (K) Deepoxy-3′-hydroxy-HT-2; (L) Deeopoxy-T-2 Tetraol by deepoxiadtion; and (M) T-2-3-glucuronide, (N) HT-2-3-glucuronide, and (O) HT-2-4-glucuronide by conjugation with glucuronic acid. UGTs: Uridine 5′-diphospho-glucuronosyltransferases [154].