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. 2020 Sep 30;8(10):390. doi: 10.3390/biomedicines8100390

Table 3.

Energy Metabolism and mitochondrial fuel oxidation.

Outcome Measures Controls PWH: 0 Weeks
p-Value:
HIV 0 w vs. Con
PWH: 12 Weeks
p-Value:
HIV 0 w vs. HIV 12 w
PWH: 20 Weeks
p-Value:
HIV 12 w vs. HIV 20 w
Fasted respiratory quotient (RQ) 0.76 ± 0.01 0.86 ± 0.04
p = 0.000
0.78 ± 0.03
p = 0.001
0.90 ± 0.05
p = 0.004
Fasted fatty acid oxidation
(mg/kg lean mass/min)
1.39 ± 0.30 0.50 ± 0.20
p = 0.007
1.39 ± 0.09
p = 0.001
Fasted carbohydrate oxidation (mg/kg lean mass/min) 0.80 ± 0.12 2.15 ± 0.34
p = 0.001
1.30 ± 0.45
p = 0.001
Fasted fatty-acid oxidation
(mg/kg/min)
0.96 ± 0.25 0.30 ± 0.11
p = 0.005
0.90 ± 0.15
p = 0.001
0.45 ± 0.23
p = 0.009
Fasted carbohydrate oxidation (mg/kg/min) 0.55 ± 0.11 1.32 ± 0.12
p = 0.001
0.84 ± 0.28
p = 0.001
1.24 ± 0.28
p = 0.002
Energy expenditure
(kcal/d)
1637 ± 299 1538 ± 269
p = 0.4
1509 ± 232
p = 0.6
1592 ± 296
p = 0.2