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. 2020 Oct 13;12(10):2967. doi: 10.3390/cancers12102967

Figure 7.

Figure 7

Effect of retinoic acid and tazarotene on chemerin and CMKLR1. (a) HepG2 cells were incubated with increasing concentrations of retinoic acid for 24 h and LDH was measured in the supernatants (n = 4); (b) HepG2 cells were incubated with increasing concentrations of tazarotene for 24 h and LDH was measured in the supernatants (n = 4); (c) HepG2 cells were incubated with retinoic acid (1 and 5 µM) for 24 h and chemerin was measured in the supernatants (n = 4); (d) HepG2 cells were incubated with tazarotene (0.1 and 0.5 µM) for 24 h and chemerin was measured in the supernatants (n = 4); (e) HepG2 cells were incubated with retinoic acid (1 and 5 µM) for 24 h and CMKLR1 was analyzed by immunoblot (n = 2); (f) HepG2 cells were incubated with tazarotene (0.1 and 0.5 µM) for 24 h and CMKLR1 was analyzed by immunoblot (n = 2). Bovine serum albumin (BSA) dissolved in EtOH and dimethylsulfoxid (DMSO) served as solvent controls. * p < 0.05, *** p < 0.001. Statistical test used: Paired t-test.