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. 2020 Oct 14;12(10):2975. doi: 10.3390/cancers12102975

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The structure of the circ2GO database. Five modules are implemented as user interfaces within circ2GO, offering multiple functionalities (blue) and their input (red) and output (green): (1) Visualization of all linear and circular isoforms for a gene including their cumulative expression in the Transcript Map as well as additional information; (2) Visualization of the expression of all circular RNA (circRNA) isoforms in the individual cell lines in a Heatmap; (3) GO search enables the searching for all genes and their circRNAs linked to a biological process, molecular function or cellular component; (4) microRNA search enables the searching for all microRNAs with binding sites on a circRNA, or all circRNA harboring binding sites for a microRNA; (5) Download options for all categories.