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DTT prevents desensitization of currents elicited by HCY, but not by NMDA. (A) Representative traces of currents recorded at Vh = −70 mV, elicited in neurons by 200 µM HCY and 200 µM NMDA in control (black) and after treatment with 1 mM DTT for 90 s (red). (B) Mean steady-state to peak (Iss/Ipeak) ratios obtained for HCY- and NMDA-elicited currents before and after treatment with DTT. **** Data are significantly different from control n = 8, p = 0.00007, Student’s t-test.
