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Simplified mechanism of glucose uptake by adipose or muscle tissue. Data combined from: [4,10,24,47,111,130]. Abbreviations defined in text, except for: JNK1/2, c-Jun N-terminal kinase 1/2; PDK1, pyruvate dehydrogenase kinase 1; IRS-1, insulin receptor substrate 1; PI3K, phosphoinositide 3-kinase; eNOS, endothelial nitric oxide synthase.
