Table 1.
Anthropometric and biochemical characteristic of studied population
| Control (n = 54) | UC (n = 42) | CD (n = 43) | P value | |
|---|---|---|---|---|
| Sex (male/female) | 42/12 | 31/11 | 28/15 | 0.373 |
| BMI (kg/m2) | 24.12 ± 3.56 | 23.45 ± 3.64 | 24.43 ± 4.61 | 0.502 |
| Normal weight / over weight | 29/25 | 26/16 | 21/22 | 0.473 |
| Age (year) | 39.02 ± 4.6 | 38.24 ± 5.32 | 38.74 ± 5.7 | 0.763 |
| SBP (mmHg) | 131.17 ± 20.79 | 133.40 ± 24.26 | 131.65 ± 23.97 | 0.887 |
| DBP (mmHg) | 81.63 ± 13.11 | 83.10 ± 14.48 | 83.16 ± 14.26 | 0.825 |
| FBG (mg/dL) | 90.26 ± 9.03 | 93.65 ± 13.27 | 94.28 ± 12.05 | 0.172 |
| Insulin (μU/mL) | 4.03 ± 0.31 | 5.66 ± 0.5 | 5.93 ± 0.64b* | 0.014 |
| HOMA-IR | 0.89 ± 0.07 | 1.31 ± 0.14 | 1.43 ± 0.17b** | 0.005 |
| TG (mg/dL) | 117.41 ± 44.83 | 128.76 ± 47.64 | 126.08 ± 38.15 | 0.409 |
| TC (mg/dL) | 157.22 ± 35.41 | 164.54 ± 47.49 | 162.25 ± 30.83 | 0.629 |
| LDL-C (mg/dL) | 94.70 ± 26.95 | 100.64 ± 35.84 | 104.93 ± 21.74 | 0.212 |
| HDL-C (mg/dL) | 43.53 ± 6.20 | 42.11 ± 9.07 | 41.46 ± 7.76 | 0.394 |
| Adiponectin (μg/mL) | 10.29 ± 3.35 | 7.88 ± 2.83a** | 7.44 ± 2.44b** | < 0.001 |
| TNF-α (pg/mL) | 16.08 ± 5.50 | 29.62 ± 7.40a** | 30.43 ± 8.25b** | < 0.001 |
| IL-6 (pg/mL) | 6.38 ± 3.51 | 8.28 ± 4.11 | 9.17 ± 4.18b** | 0.002 |
| Metrnl (pg/mL) | 107.52 ± 35.33 | 76.93 ± 27.92a** | 85.25 ± 36.55b** | < 0.001 |
Data are presented as Mean ± SD
One way ANOVA and Tukey’s multiple comparisons test were used for comparison of quantitative variables
Abbreviations: UC ulcerative colitis, CD Crohn’s disease, SBP systolic blood pressure, DBP diastolic blood pressure, FBG fasting blood glucose, HOMA-IR homeostasis model assessment of insulin resistance, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, TC total cholesterol, TG triglyceride
a Comparison between control and UC
b Comparison between control and CD
*P < 0.05
**P < 0.01