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Folate supplementation significantly improved Mini-Mental State Examination (MMSE) in the short-term. The MMSE score improved from 20.1 ± 4.7 to 22.2 ± 4.3 (p < 0.001, effect size 0.59) 28 days to 63 days after folate supplementation. Bar: ± SD. The MMSE score following a normal distribution was analyzed by the Student’s t-test.
