Table 1.
Mortality risk within 12 months of HD initiation according to nutritional indicators of malnutrition.
| Reference | Sample Size (n) | Predictors of Mortality | |||
|---|---|---|---|---|---|
| Bradbury et al., 2007 [34] | 4802 | Months | BMI < 20 kg/m 2 | Ser.Alb < 3.5 g/L | |
| (AHR 95% CI) | |||||
| <4 | 0.98 (0.67–1.44) | 1.57 (1.18–2.09) | |||
| 4–12 | 1.38 (0.98–1.94) | 1.27 (1.00–1.63) | |||
| >12 | 1.19 (0.93–1.53) | 1.41 (1.17–1.70) | |||
| Lukowsky et al., 2012 [20] | 18,707 | Months |
BMI increase by 2
index points |
Ser.Alb < 3.5 g/L | nPCR > 1.0 g/kg/day |
| (AHR 95% CI) | |||||
| <3 | 0.92 (0.90–0.94) | 2.56 (2.30–2.84) | 1.21 (1.06–1.38) | ||
| 4–6 | 0.93 (0.91–0.95) | 2.04 (1.81–2.31) | 0.96 (0.80–1.14) | ||
| 7–12 | 0.94 (0.92–0.96) | 1.89 (1.70–2.10) | 0.89 (0.74–1.07) | ||
| McQuillan et al., 2015 [22] | 4807 | Months | BMI <18.5 kg/m2 | ||
| <3 | AHR (95% CI) = 4.22 (3.12–5.17) | ||||
| Murray et al., 2018 [35] | 227 | Parameters | CPH | p-value | |
| BMI | 0.97 (0.85–1.11) | 0.625 | |||
| Ser.Alb | 0.40 (0.12–1.39) | 0.149 | |||
| Undefined malnutrition (using clinical judgment) | 4.70 (0.25–88.78) | 0.302 | |||
Abbreviations: AHR, adjusted hazard ratio; BMI, body mass index; CI, confidence interval; CPH, Cox proportional hazard; HD, hemodialysis; nPCR, normalized protein catabolic rate; Ser.Alb, serum albumin.