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. 2020 Oct 14;12(10):969. doi: 10.3390/pharmaceutics12100969

Table 8.

Coefficient estimates demonstrating the response change per unit change in factor value when the remaining factors remain constant. The intercept is the average response of the runs. The coefficients are normalized by the average. For orthogonal factors the VIFs are 1; VIFs > 1 are the indications of multi-collinearity.

Factor Coefficient Estimate df Standard Error 95% CI Low 95% CI High VIF
Intercept −11.57 1 0.3766 −12.40 −10.74
A 0.9689 1 0.4595 −0.0424 1.98 1.02
B 0.9543 1 0.4490 −0.0339 1.94 1.00
C 0.3957 1 0.3766 −0.4332 1.22 1.02
AB −0.6684 1 0.5477 −1.87 0.5371 1.02
AC 0.4974 1 0.4554 −0.5050 1.50 1.00
BC −1.12 1 0.4484 −2.11 −0.1381 1.02