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. 2020 Oct 15;17(20):7506. doi: 10.3390/ijerph17207506

Table 1.

Distributions of the PEAR1A, MRVI1, and GP6 genotypes and alleles in patients with unstable angina and controls.

Control Group Unstable Angina p Value ^ p Value ^ OR (95% CI)
n % n %
PEAR1A
rs12566888
Genotype
GG 152 80.85% 199 83.97% 0.57 TT+GT vs. GG 0.40 0.81 (0.49–1.33)
GT 34 18.09% 37 15.61% TT vs. GT+GG 0.43 0.39 (0.04–4.38)
TT 2 1.06% 1 0.42% TT vs. GG 0.42 0.38 (0.03–4.25)
GT vs. GG 0.48 0.83 (0.50–1.39)
TT vs. GT 0.52 0.46 (0.04–5.30)
Allele
G 338 89.89% 435 91.77% T vs. G 0.34 0.80 (0.50–1.27)
T 38 10.11% 39 8.23%
MRVI1
rs7940646
genotype
CC 80 42.33% 100 40.65% 0.82 TT+CT vs. CC 0.72 1.07 (0.73–1.57)
CT 86 45.50% 119 48.37% TT vs. CT+CC 0.70 0.89 (0.49–1.61)
TT 23 12.17% 27 10.98% TT vs. CC 0.84 0.94 (0.50–1.76)
CT vs. CC 0.62 1.11 (0.74–1.66)
TT vs. CT 0.60 0.85 (0.46–1.58)
Allele
C 246 65.08% 319 64.84% T vs. C 0.94 1.01 (0.76–1.34)
T 132 34.92% 173 35.16%
GP6
rs1671152
genotype
GG 157 83.07% 206 83.74% 0.49 TT+GT vs. GG 0.85 0.95 (0.57–1.59)
GT 30 15.87% 34 13.82% TT vs. GT+GG 0.29 2.34 (0.47–11.71)
TT 2 1.06% 6 2.44% TT vs. GG 0.30 2.29 (0.46–11.48)
GT vs. GG 0.59 0.86 (0.51–1.47)
TT vs. GT 0.24 2.65 (0.50–14.12)
Allele
G 344 91.01% 446 90.65% T vs. G 0.86 1.04 (0.66–1.66)
T 34 8.99% 46 9.35%

^ χ2 test; Alleles: A–adenine, C–cytosine, G–guanine, T–thymine; HWE: control group p = 1.00, unstable angina p = 1.00 for PEAR1A rs12566888; HWE: control group p = 1.00, unstable angina p = 0.40 for MRVI1 rs7940646; HWE: control group p = 0.65, unstable angina p = 0.011 for GP6 rs1671152.