. 2020 Oct 15;17(20):7506. doi: 10.3390/ijerph17207506

Table 2.

Distributions of the PIK3CG, JMJD1C, and SHH genotypes and alleles in patients with unstable angina and controls.

	Control Group		Unstable Angina		p Value ^{^}		p Value ^{^}	OR (95% CI)
	n	%	n	%	p Value ^{^}		p Value ^{^}	OR (95% CI)
PIK3CG rs342286 genotype
AA	55	29.26%	65	26.75%	0.76	GG+AG vs. AA	0.56	1.13 (0.74–1.73)
AG	98	52.13%	127	52.26%		GG vs. AG+AA	0.54	1.16 (0.72–1.88)
GG	35	18.62%	51	20.99%		GG vs. AA	0.46	1.23 (0.70–2.16)
						AG vs. AA	0.69	1.10 (0.70–1.71)
						GG vs. AG	0.65	1.12 (0.68–1.86)
Allele
A	208	55.32%	257	52.88%		G vs. A	0.48	1.10 (0.84–1.45)
G	168	44.68%	229	47.12%		G vs. A	0.48	1.10 (0.84–1.45)
JMJD1C rs10761741 genotype
GG	68	36.36%	86	35.10%	0.70	TT+GT vs. GG	0.79	1.06 (0.71–1.57)
GT	89	47.59%	112	45.71%		TT vs. GT+GG	0.40	1.24 (0.75–2.06)
TT	30	16.04%	47	19.18%		TT vs. GG	0.45	1.24 (0.71–2.16)
						GT vs. GG	0.98	1.00 (0.65–1.52)
						TT vs. GT	0.42	1.24 (0.73–2.13)
Allele
G	225	60.16%	284	57.96%		T vs. G	0.51	1.10 (0.83–1.44)
T	149	39.84%	206	42.04%		T vs. G	0.51	1.10 (0.83–1.44)
*SHH* rs2363910 genotype
GG	155	82.01%	199	81.22%	0.93	TT+GT vs. GG	0.83	1.05 (0.65–1.72)
GT	33	17.46%	44	17.96%		TT vs. GT+GG	0.72	1.55 (0.14–17.19)
TT	1	0.53%	2	0.82%		TT vs. GG	0.72	1.56 (0.14–17.34)
						GT vs. GG	0.88	1.04 (0.63–1.71)
						TT vs. GT	0.74	1.50 (0.13–17.25)
Allele
G	343	90.74%	442	90.20%		T vs. G	0.79	1.06 (0.67–1.68)
T	35	9.26%	48	9.80%		T vs. G	0.79	1.06 (0.67–1.68)

^ χ² test; HWE: control group p = 0.55, unstable angina p = 0.52 for PIK3CG rs342286; HWE: control group p = 1.00, unstable angina p = 0.36 for JMJD1C rs10761741; HWE: control group p = 1.00, unstable angina p = 1.00 for SHH rs2363910.