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. 2020 Oct 15;17(20):7506. doi: 10.3390/ijerph17207506

Table 2.

Distributions of the PIK3CG, JMJD1C, and SHH genotypes and alleles in patients with unstable angina and controls.

Control Group Unstable Angina p Value ^ p Value ^ OR (95% CI)
n % n %
PIK3CG rs342286
genotype
AA 55 29.26% 65 26.75% 0.76 GG+AG vs. AA 0.56 1.13 (0.74–1.73)
AG 98 52.13% 127 52.26% GG vs. AG+AA 0.54 1.16 (0.72–1.88)
GG 35 18.62% 51 20.99% GG vs. AA 0.46 1.23 (0.70–2.16)
AG vs. AA 0.69 1.10 (0.70–1.71)
GG vs. AG 0.65 1.12 (0.68–1.86)
Allele
A 208 55.32% 257 52.88% G vs. A 0.48 1.10 (0.84–1.45)
G 168 44.68% 229 47.12%
JMJD1C rs10761741
genotype
GG 68 36.36% 86 35.10% 0.70 TT+GT vs. GG 0.79 1.06 (0.71–1.57)
GT 89 47.59% 112 45.71% TT vs. GT+GG 0.40 1.24 (0.75–2.06)
TT 30 16.04% 47 19.18% TT vs. GG 0.45 1.24 (0.71–2.16)
GT vs. GG 0.98 1.00 (0.65–1.52)
TT vs. GT 0.42 1.24 (0.73–2.13)
Allele
G 225 60.16% 284 57.96% T vs. G 0.51 1.10 (0.83–1.44)
T 149 39.84% 206 42.04%
SHH
rs2363910
genotype
GG 155 82.01% 199 81.22% 0.93 TT+GT vs. GG 0.83 1.05 (0.65–1.72)
GT 33 17.46% 44 17.96% TT vs. GT+GG 0.72 1.55 (0.14–17.19)
TT 1 0.53% 2 0.82% TT vs. GG 0.72 1.56 (0.14–17.34)
GT vs. GG 0.88 1.04 (0.63–1.71)
TT vs. GT 0.74 1.50 (0.13–17.25)
Allele
G 343 90.74% 442 90.20% T vs. G 0.79 1.06 (0.67–1.68)
T 35 9.26% 48 9.80%

^ χ2 test; HWE: control group p = 0.55, unstable angina p = 0.52 for PIK3CG rs342286; HWE: control group p = 1.00, unstable angina p = 0.36 for JMJD1C rs10761741; HWE: control group p = 1.00, unstable angina p = 1.00 for SHH rs2363910.