Figure 3.

Genes studied in ≥ 3 prognostic candidate marker studies. Each row represents a candidate gene study, and each column represents a gene for which three or more studies have investigated its methylation profile as a prognostic marker of PCa. The number in brackets indicates the number of studies the gene has been examined in. For each of the 26 studies, genes that were investigated have been highlighted: grey = examined in study but no significant associations were found; faded green = significant associations found in univariate analysis only; light green = significant associations observed in multivariate analysis only; green = significant associations reported in both univariate and multivariate analysis.