Table 1.
Animal Model/Human Disease | Pathogen | Route and Schedule of Phage Administration | Reference |
---|---|---|---|
Galleria mellonella larvae mouse |
Acinetobacter baumannii | single injection single ip MOI of 100 |
[6] |
mouse | Acinetobacter baumannii | single ip 109 | [7] |
mouse | Acinetobacter baumannii | single ip MOI of 0.1–10 | [8] |
mouse | Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae, Pseudomonas aeruginosa, Citrobacter freundii, Moraxella catarrhalis | single ip MOI of 0.001–2 | [9] |
mouse | Pseudomonas aeruginosa | single ip 109 | [10] |
Di George syndrome with septicemia | Pseudomonas aeruginosa | iv for 3 days 3 × 105 every 6 h | [15] |
Acute kidney failure with septicemia | Pseudomonas aeruginosa | iv for 10 days concentration not given | [16] |
Endocarditis with septicemia (13 patients) | Staphylococcus aureus | iv for 14 days | [17] |
Disseminated mycobacterial infection | Mycobacterium abscessus | iv for 32 weeks 109 every 12 h for 32 weeks | [18] |
Endocarditis with septicemia (119 patients) | Staphylococcus aureus | Anti-staph lysin iv 0.12–0.25 mg/kg for 14 days | [27] |