Table 4.
Biological evolution between baseline, 3 months, and 6 months.
| Difference between Baseline and 3 Months | Difference between Baseline and 6 Months | |
|---|---|---|
| Hemoglobin (g/dL), med [Q1–Q3] | −0.4 [−1.0–0.1] ** | −0.8 [−1.1–0.1] * |
| Platelets (/mm3), med [Q1–Q3] | 56,000 [6000–82,000] * | 38,500 [−12,000–76,000] |
| Leukocytes (/mm3), med [Q1–Q3] | −300.0 [−1800–500] * | −105.0 [−1410–420] |
| Polynuclear neutrophils (/mm3), med [Q1–Q3] | −488.5 [−1229.5–516.5] * | 85.5 [−1040–655] |
| Eosinophilic cells (/mm3), med [Q1–Q3] | −40.5 [−91–145] * | −24.0 [−91–−1.0] |
| Lymphocytes (/mm3), med [Q1–Q3] | 41.0 [−400–792] * | −181.5 [–501–430] |
| ESR, med [Q1–Q3] | 0.0 [−4.0–4.0] * | −0.5 [−5.0–3.0] |
| CRP, med [Q1–Q3] | −1.1 [−5.9–0.0] * | −3.1 [−7.2–0.0] |
| Aspartate transaminase (UI/L), med [Q1–Q3] | 3.0 [−3.0–7.0] ** | 4.0 [−2.0–6.0] |
| Alanine transaminase (UI/L), med [Q1–Q3] | 1.0 [−31.0–24.0] ** | 0.0 [−6.0–7.0] |
| Creatinine (µmol/L), med [Q1–Q3] | 2.6 [−2.5–7.0] ** | 0.0 [−4.5–7.9] |
| Creatinine clearance (mL/min), med [Q1–Q3] | −2.3 [−7.8–7.3] ** | 0.0 [−11.0–7.7] |
| Total cholesterol (g/L), med [Q1–Q3] | 0.1 [−0.2–0.2] † | 0.1 [−0.1–0.2] † |
| Triglycerides (g/L), med [Q1–Q3] | 0.0 [−0.6–0.2] † | −0.3 [−0.6–0.2] † |
| LDL cholesterol (g/L), med [Q1–Q3] | 0.0 [−0.2–0.2] † | 0.0 [−0.1–0.1] † |
| HDL cholesterol (g/L), med [Q1–Q3] | 0.0 [−0.4–0.4] † | 0.0 [0.0–0.1] † |
med: median value; Q1: first quartile; Q3: third quartile; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; LDL: low-density lipoprotein; HDL: high-density lipoprotein; * missing data for 7 patients; ** missing data for 10 patients; † missing data for 25 patients.