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. 2020 Oct 27;13:10877–10887. doi: 10.2147/OTT.S267915

Figure 4.

Figure 4

MiR-497-5p mediated Atg14 to induce autophagy. (A) MiR-497-5p had targeted binding sites with ATG14. (B) Dual-luciferase reporter confirmed the targeting relationship between miR-497-5p and ATG14. (C) Relative expression of miR-497-5p in cells after transfection. (D) Drug resistance of BGC823/DDP cells after transfection. (E) Drug resistance of SFC7901/DDP cells after transfection. (F) Apoptosis rate after transfection. (G) ATG14, LC3-I, LC3-II protein expression levels in cells after transfection. *Indicates P<0.05, **Indicates P<0.01, and ***Indicates P<0.001.