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. 2020 Oct 17;11(10):1217. doi: 10.3390/genes11101217

Table 3.

Aspergillus flavus Cyp51A analysis. The sequence of A. flavus NRRL3357 type strain was used as Reference. In bold the A. flavus azole resistant strains.

Strains A * Aspergillus flavus Cyp51A
c132t c165t c342t g390a t546c g595a c641t t723c c738t t907c t927c g966t a985g c1065t t1164c c1368t g1371a
F44 P55 G114 K130 F182 A199T P214L 1 Y241 N246 L303 P309 K322N T329A H355 P388 N456 L456
CM7668 R c165t g390a t546c c641t t1164c
CM8087 R c165t g390a t546c a985g t1164c
CM8098 S c165t g390a t546c a985g t1164c
CM9165 S c165t t546c t723c t1164c
CM9174 S c165t g390a t546c a985g t1164c
CM9189 S c165t g390a t546c t1164c
CM9195 S c165t g390a t546c t1164c
CM9228 S t546c t907c g966t t1164c
CM9267 S c165t g390a t546c t1164c
CM9298 S c132t c165t c342t g390a t546c t927c t1164c c1368t
CM9326 R c165t g390a t546c t1164c
CM9329 S c165t g390a t546c t1164c
CM9331 S c165t g390a t546c t1164c
CM9684 S c165t g390a t546c a985g t1164c
TPH642 S c165t g390a t546c t1164c
TPH968 S c165t g390a t546c t1164c
TPH992 S c165t g390a t546c t1164c
TPH1004 S c165t g390a t546c t1164c
TPH1115 S c165t g390a t546c t1164c
TPH1179 S c165t g390a t546c t1164c
ATCC2004304 S c165t g390a t546c g595a c1065t t1164c c1368t g1371a
A. oryzae RIB40 - c165t g390a t546c g595a c1065t t1164c c1368t g1371a
A. flavus AF70 - c165t g390a t546c c738t t1164c c1368t
Protein F44 P55 G114 K130 F182 A199T P214L 1 Y241 N246 L303 P309 K322N T329A H355 P388 N456 L456

* A, azole drugs profile, S susceptible, R Resistant. 1 This mutation was previously described in a recent work [36].