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The scope of the cellular ubiquitome. (A) The number of ubiquitinated proteins and sites reported by key studies in the last 20 years [10,12,14,15,17,19,20,21,22,23]. (B–D) Insight from the PhosphositePlus database [24] on ubiquitinated proteins: (B) the most frequently ubiquitinated protein domains; (C) the overlap of studies reporting ubiquitination sites; and (D) the frequency of the number of ubiquitination sites per protein.
