Table 7.
Effect of citral on biochemical parameters of hepatic function in eutrophic (SD) and obese mice (HFD).
| Groups | AST (UI/L) | ALT (UI/L) | Alkaline Phosphatase (UI/L) | GGT (UI/L) | ||||
|---|---|---|---|---|---|---|---|---|
| SD | HFD | SD | HFD | SD | HFD | SD | HFD | |
| Tween 80 + Saline | 113.60 ± 42.60 | <2.0 | 63.29 ± 9.31 | 57.17 ± 4.01 | 37.57 ± 5.21 | 12.75 ± 0.48 a | <1.0 | <1.0 |
| Tween 80 + LPS | 110.70 ± 39.61 | <2.0 | 51.71 ± 14.91 | 96.14 ± 16.21 | 17.00 ± 3.01 * | 11.57 ± 9.64 | <1.0 | <1.0 |
| IBU 100 + LPS | <2.0 | <2.0 | 72.83 ± 11.73 | 124.6 ± 29.08 | 21.40 ± 5.79 | 23.00 ± 0.01 | <1.0 | <1.0 |
| Citral 300 + Saline | 107.40 ± 44.79 | <2.0 | 54.29 ± 11.26 | 92.25 ± 16.23 | 21.00 ± 1.86 | 10.67 ± 1.02 | <1.0 | <1.0 |
| Citral 25 + LPS | 111.20 ± 59.58 | <2.0 | 81.83 ± 18.31 | 74.40 ± 6.56 | 22.00 ± 2.77 | 13.86 ± 0.86 | <1.0 | <1.0 |
| Citral 100 + LPS | 133.30 ± 61.01 | <2.0 | 85.17 ± 26.22 | 227.30 ± 60.96 * | 16.33 ± 2.09 * | 17.43 ± 3.12 | <1.0 | <1.0 |
| Citral 300 + LPS | 114.10 ± 49.78 | <2.0 | 59.71 ± 4.59 | 95.86 ± 20.26 | 26.14 ± 3.73 | 13.67 ± 2.22 | <1.0 | <1.0 |
All data are expressed as mean ± SEM for n = 6–8 per group. One-way ANOVA followed by Dunnett’s test; * p < 0.05 vs. Tween 80 + saline. Two-way ANOVA followed by Bonferroni’s test; a = p < 0.05 compared to the SD mice.