Table 2.
Characteristics of 52 patients with nonalcoholic fatty liver disease at the initial and second biopsies.
| Variable n = 52 | At Initial Biopsy | At Second Biopsy | p |
|---|---|---|---|
| Sex, male | 22 (42.3%) | ||
| Age, years | 68 (21–83) | ||
| Hyperlipidemia | 33 (63.5%) | ||
| T2DM | 26 (50.0%) | ||
| Hypertension | 24 (46.2%) | ||
| BMI, kg/m2 | 26.4 (18.9––43.0) | 26.6 (19.0–49.5) | 0.486 |
| Albumin, g/dL | 4.3 (3.2–4.9) | 4.1 (3.4–5.1) | 0.001 |
| AST, IU/L | 57 (22–186) | 38 (15–211) | <0.001 |
| ALT, IU/L | 83 (20–358) | 46 (7–251) | <0.001 |
| GGT, IU/L | 73 (22–306) | 45 (8–316) | 0.009 |
| Platelet count, ×103/μL | 207 (105–417) | 195 (93–403) | 0.040 |
| Total cholesterol, mg/dL | 201 (117–292) | 191 (93–436) | 0.203 |
| Triglycerides, mg/dL | 153 (71–559) | 130 (60–351) | 0.022 |
| LDL-C, mg/dL | 104 (43–225) | 124 (43–209) | 0.035 |
| HDL-C, mg/dL | 50 (22–85) | 51 (28–95) | 0.748 |
| FPG, mg/dL | 94 (60–260) | 96 (65–182) | 0.664 |
| FIB-4 index | 2.12 (0.31–9.04) | 2.20 (0.26–3.14) | 0.973 |
| Type IV collagen 7s, ng/mL | 5.3 (2.7–13.0) | 4.4 (2.6–9.5) | 0.002 |
| Fibrosis stage (0/1/2/3/4) | 0/24/14/14/0 | 2/18/21/8/3 |
Abbreviations are defined in Table 1.