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LET versus depth in tissue for a single SOBP of p, He, C, and O providing a uniform physical dose (2 Gy). The grey area represents the tumor region, a 2.5 × 2.5 × 2.5 cm3 volume centered at 8 cm in water. The yellow and orange lines are 100 and 20 keV/μm level, respectively. Figure from [15], distributed under Creative Commons CC-BY.
