Table 2.
EDSS, ARR1, and ARR2 means and standard deviations in the HLA-DRA SNP genotypes.
| Polymorphism | Genotype | Mean±SD | p value |
|---|---|---|---|
| EDSS | |||
| DelINSrs9281809 | -/-AACTAACT | 1.87±1.65 | 0.366 |
| AACTAACT/AACTAACT | 2.90±1.35 | ||
| INS/- | 2.82±1.24 | ||
| rs4935356 | A/A | 1 | 0.104 |
| G/A | 4±0.5 | ||
| G/G | 2.84±1.34 | ||
| G/T | 2.68±1.15 | ||
| T/A | 5 | ||
| T/T | 1.87±1.65 | ||
| rs3135390 | A/A | 2.87±1.32 | 0.092 |
| C/A | 3±1.25 | ||
| C/C | 1.16±1.04 | ||
| rs4935354 | C/C | 1.87±1.65 | 0.366 |
| C/T | 2.82±1.24 | ||
| T/T | 2.9±1.35 | ||
| rs3177928 | A/A | 1 | 0.090 0.070 |
| G/A | 3.8±1.1 | ||
| G/G | 2.70±1.3 | ||
| rs7194 | A/A | 2.90±1.35 | 0.366 |
| G/A | 2.46±1.29 | ||
| G/G | 1.87±1.65 | ||
| rs7195 | A/A | 1.87±1.65 | 0.366 |
| G/A | 2.82±1.24 | ||
| G/G | 2.90±1.35 | ||
| rs1131541 | T/A | 2.85±1.21 | .883 |
| T/T | 2.77±1.37 | ||
| rs7196 | A/A | 1.16±1.04 | 0.090 |
| T/A | 3.45±1.31 | ||
| T/T | 2.85±1.31 | ||
| rs7197 | C/C | 2.87±1.32 | 0.088 |
| C/T | 3±1.23 | ||
| T/T | 0.75±1.06 | ||
| rs1051336 | G/A | 2.85±1.21 | 0.441 |
| G/G | 2.77±1.37 | ||
| rs111471704 | T/A | 2.5 | 0.831 |
| T/T | 2.79±1.35 | ||
| rs1157343109 | T/T | 2.78±1.34 | - |
| rs1041885 | T/T | 2.78±1.34 | - |
| ARR1 | |||
| DelINSrs9281809 | -/-AACTAACT | 0.12±0.20 | 0.224 |
| AACTAACT/AACTAACT | 0.43±0.67 | ||
| INS/- | 0.23±0.32 | ||
| rs4935356 | A/A | 0 | 0.423 |
| G/A | 0.22±0.25 | ||
| G/G | 0.46±0.70 | ||
| G/T | 0.25±0.32 | ||
| T/A | 0 | ||
| T/T | 0.05±0.11 | ||
| rs3135390 | A/A | 0.39±0.62 | 0.472 |
| C/A | 0.23±0.33 | ||
| C/C | 0.06±0.12 | ||
| T/A | 0 | ||
| rs4935354 | C/C | 0.05±0.11 | 0.190 |
| C/T | 0.24±0.32 | ||
| T/T | 0.43±0.67 | ||
| rs3177928 | A/A | 0 | 0.635 |
| G/A | 0.18±0.24 | ||
| G/G | 0.360.58 | ||
| rs7194 | A/A | 0.43±0.67 | 0.190 |
| G/A | 0.24±0.32 | ||
| G/G | 0.05±0.11 | ||
| Rs7195 | A/A | 0.05±0.11 | 0.190 |
| G/A | 0.24±0.32 | ||
| G/G | 0.43±0.67 | ||
| rs1131541 | T/A | 0.24±0.33 | 0.601 |
| T/T | 0.35±0.58 | ||
| rs7196 | A/A | 0.06±0.12 | 0.526 |
| T/A | 0.30±0.50 | ||
| T/T | 0.37±0.59 | ||
| rs7197 | C/C | 0.39±0.61 | 0.361 |
| C/T | 0.23±0.33 | ||
| T/T | 0.06±0.12 | ||
| rs1051336 | G/A | 0.25±0.32 | 0.612 |
| G/G | 0.35±0.58 | ||
| rs111471704 | T/A | 1 | 0.239 |
| T/T | 0.33±0.55 | ||
| rs1157343109 | T/T | 0.34±0.55 | - |
| rs1041885 | T/T | 0.34±0.55 | - |
| ARR2 | |||
| DelINSrs9281809 | -/-AACTAACT | 0.12±.20 | 0.719 |
| AACT/AACT | 0.37±0.51 | ||
| AACTAACT/AACTAACT | 0.50±0.68 | ||
| INS/- | |||
| rs493535 | A/A | 1 | 0.849 |
| G/A | 0.40±0.61 | ||
| G/G | 0.46±0.70 | ||
| G/T | 0.37±0.51 | ||
| T/A | 0 | ||
| T/T | 0.53±0.50 | ||
| rs3135390 | A/A | 0.48±0.64 | 0.733 |
| C/A | 0.35±0.58 | ||
| C/C | 0.41±0.49 | ||
| T/A | 1 | ||
| rs4935354 | C/C | 0.53±0.50 | 0.632 |
| C/T | 0.36±0.51 | ||
| T/T | 0.5±0.68 | ||
| rs3177928 | A/A | 1 | 0.611 |
| G/A | 0.33±0.57 | ||
| G/G | 0.46±0.62 | ||
| rs7194 | A/A | 0.5±0.68 | 0.632 |
| A/G | 0.36±0.51 | ||
| G/G | 0.53±0.50 | ||
| Rs7195 | A/A | 0.53±0.50 | 0.632 |
| G/A | 0.36±0.51 | ||
| G/G | 0.50±0.68 | ||
| rs1131541 | T/A | 0.48 ± 0.45 | 0.923 |
| T/T | 0.45 ± 0.63 | ||
| rs7196 | A/A | 0.41±0.49 | 0.907 |
| A/T | 0.41±0.55 | ||
| T/T | 0.48±0.65 | ||
| rs7197 | C/C | 0.49±0.63 | 0.743 |
| C/T | 0.35±0.58 | ||
| T/T | 0.41±0.49 | ||
| rs1051336 | G/A | 0.42±0.45 | 0.864 |
| G/G | 0.46±0.63 | ||
| rs111471704 | T/A | - | - |
| T/T | 0.45±0.61 | ||
| rs1157343109 | T/T | 0.45±0.61 | - |
| rs1041885 | T/T | 0.45±0.61 | - |