Table 4.
Key changes in practice | 10-year incidence n (%age of available data)$ | Available data n (%age) | Missing data n (%age) | Unadjusted odds (95% CI) | Adjusted odds (95% CI)! |
---|---|---|---|---|---|
Total infants | 948 | ||||
Surfactant during initial resuscitation | 855 (90.2) | 948 (0.0) | 0 (0.0) | 0.94 (0.87, 1.01) | 0.93 (0.86, 1.01)1,3,7 |
Surfactant at any time (absolute) | 894 (94.3) | 948 (0.0) | 0 (0.0) | 0.93 (0.84, 1.03) | 0.90 (0.81, 1.00)1,3,4,* |
Any non-invasive ventilation during resuscitation (face-mask, CPAP) | 842 (90.6) | 929 (98.0) | 19 (2.0) | 1.28 (1.17, 1.39)* | 1.26 (1.15, 1.38)3,7,* |
Any non-invasive ventilation after resuscitation | 733 (81.6) | 898 (94.7) | 50 (5.3) | 1.03 (0.97, 1.09) | 1.03 (0.97, 1.10)1,2 |
Any mechanical ventilation during resuscitation | 871 (92) | 947 (99.9) | 1 (0.1) | 0.90 (0.82, 0.98)* | 0.89 (0.81, 0.97)1,3,7,* |
Any mechanical ventilation after initial resuscitation | 878 (97.8) | 898 (94.7) | 50 (5.3) | 0.80 (0.67, 0.95)* | 0.80 (0.68, 0.96)1,* |
Odds (95% CI) are for trend, calculated by logistic regression models with the year of birth as a continuous variable, and adjusted for gestational age at birth1, sex2, centre3 and outborn-status4, along with the interaction terms gestation*year of birth5, gestation*gender (1)6 and centre of care*outborn-status (1)7.
$All analysis was conducted after excluding missing data.
!Superscript numbers indicate significant independent variable on adjusted analysis as numbered above.