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. 2020 Oct 19;12(10):3196. doi: 10.3390/nu12103196

Table 4.

Multiple linear regression models to explore the relationship between vitamin D during pregnancy (first and third trimesters) and the Bayle Scales of Infant Development-III (BSID-III) cognitive scale scores at 40 days postpartum.

CRITERIA: Cognitive Scales
IOM Levels First Trimester of Pregnancy Third Trimester of Pregnancy <20 nmol/L Levels First Trimester of Pregnancy Third Trimester of Pregnancy
Unadjusted Models Beta
p 		Beta
p 		Beta
p 		Beta
p
Vitamin D (<30 vs. 30–50 nmol/L) 0.045
0.426		 −0.008
0.918		 Vitamin D (<20 vs. 20–50 nmol/L) 0.001
0.990		 0.022
0.801
Vitamin D (<30 vs. >50 nmol/L) 0.150
0.008		 −0.015
0.836		 Vitamin D (<20 vs. >50 nmol/L) 0.134
0.050		 0.002
0.979
R2c*100 = 1.4% R2c*100 = −0.9% R2c*100 = 1.2% R2c*100 = −0.9%
F2.364 = 3.627 F2.222 = 0.022 F2.364 = 3.304 F2.222 = 0.048
p = 0.028 p = 0.978 p = 0.038 p = 0.953
Adjusted models
Vitamin D (<30 vs. 30–50 nmol/L) 0.051
0.354		 −0.017
0.809		 Vitamin D (<20 vs. 20–50 nmol/L) −0.001
0.986		 0.057
0.508
Vitamin D (<30 vs. >50 nmol/L) 0.141
0.011		 −0.001
0.985		 Vitamin D (<20 vs. >50 nmol/L) 0.121
0.074		 0.043
0.619
Gestational age 0.175
0.001		 0.258
0.001		 Gestational age 0.174
0.001		 0.262
0.001
Folate 0.103
0.046		 Folate 0.102
0.050
R2c*100 = 4.6% R2c*100 = 5.3% R2c*100 = 4.3% R2c*100 = 5.5%
F4.364 = 5.353 F3.222 = 5.179 F4.364 = 5.126 F3.222 = 5.316
p = 0.001 p = 0.002 p = 0.001 p = 0.001

Models adjusted for the following variables: vitamin D levels (first or third trimester); mother’s age (years), family socioeconomic level (score), tobacco consumption (yes/no), type of feeding (formula/breastfeeding), gestational age at birth (weeks), type of delivery (eutocic/dystocic), child’s gender (0: boy/1: girl), mother–child interaction score, mother anxiety state score (first or third trimester), ferritin levels (μg/mL) (first or third trimester), folates (μg/mL), B12 vitamin levels (μg/mL) (first or third trimester), and diet quality (first or third trimester). The models for the third trimester were adjusted for the first trimester vitamin D levels. IOM: Institute Of Medicine. R2c*100: Corrected R square multiplied by 100.