Table 2.
Serious compilations and prognosis of critically ill children with haematological malignancies
| All patients (n = 37) |
Standard-dose group (>0.1 mg/kg/day) (n = 22) |
Low-dose group (≤0.1 mg/kg/day) (n = 15) |
P value | |
|---|---|---|---|---|
| Incidence of serious complications | 84% (31) | 77% (17) | 93% (14) | 0.397 |
| TLS | 73% (27) | 73% (16) | 73% (11) | 1.000 |
| Laboratory TLS | 30% (11) | 23% (5) | 40% (6) | 0.417 |
| Clinical TLS | 43% (16) | 50% (11) | 33% (5) | 0.500 |
| AKI | 59% (22) | 64% (14) | 53% (8) | 0.775 |
| Stage 1 | 11% (4) | 9% (2) | 13% (2) | |
| Stage 2 | 16% (6) | 14% (5) | 7% (1) | |
| Stage 3 | 32% (12) | 32% (7) | 33% (5) | |
| Requirement of RRT | 24% (9) | 23% (5) | 27% (4) | 1.000 |
| Respiratory failure | 24% (9) | 27% (6) | 20% (3) | 0.908 |
| Heart failure | 11% (4) | 14% (3) | 7% (1) | 0.896 |
| DIC | 16% (6) | 14% (3) | 20% (3) | 0.670 |
| Others | 14% (5) | 9% (2) | 20% (3) | 0.643 |
| Prognosis | ||||
| 7-day mortality | 14% | 9% | 20% | 0.643 |
| 28-day mortality | 16% | 14% | 20% | 0.951 |
| LOS in ICU (d) | 8.95±4.77 | 9.41±4.71 | 8.27±4.93 | 0.482 |
| Costs in ICU stay ($) | 10003±4949 | 10024±3651 | 9971±6556 | 0.978 |
TLS tumour lysis syndrome, AKI acute kidney injury, RRT renal replacement therapy, DIC Disseminated intravascular coagulation, LOS length of stay, ICU intensive care unit