Table 3.
Author | No. of eyes/patients | Country | Predisposing medical conditions % | Focus of infection % | Positive blood culture % | Positive vitreous culture % | Intravitreal antibiotic/antifungal (and percentage of repeated injections) | Pars plana vitrectomy % | Anatomical success % | Functional success % (defined as final VA >20/400) | Comments |
---|---|---|---|---|---|---|---|---|---|---|---|
Ang et al. [54] | 71/61 | Singapore | Diabetes 55.7 | Hepatobiliary 77.5 Urinary 9.9 |
92.9 | 43.6 | 84.5 | 26.8 | 73.2 | 22.5 | Risk factors for poor visual outcome: Presence of hypopyon Unilateral involvement Interval from sepsis onset to ocular symptoms Panophtalmia |
| |||||||||||
Odouard et al. [57] | 6/4 | Australia | Diabetes 50 | Hepatobiliary 100 | 75 | 50 | 100 (100) | 100 | 83.3 | 50 | All patients were of Southeast Asian ethnicity |
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Chung et al. [32] | 24/19 | Hong Kong | Diabetes 52.6 Liver cirrhosis 15.8 |
Sepsis 100 Liver abscess 94.7 Empyema 15.7 |
94.7 | 37.5 | 89.4 | 15.8 | 40 | 16.6 | Mortality 21.1% |
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Shields et al. [27] | 12/10 | USA | Diabetes 70 | Liver abscess 40 Pulmonary 30 Soft tissue 20 |
66.6 | 25 | 100 | 8.1 | 58.3 | 33.3 (42 VA > CF) | 30% of patients were not of Asian ethnicity |