Table 10.
Effect of 100-400 mg/kg/day of IGESE on cardiovascular risk indices (atherogenic index (AI) and coronary risk index (CRI)) values in DOX-intoxicated rats.
Treatment groups | TC ÷ HDL − c (AI) | LDL − c ÷ HDL − c (CRI) |
---|---|---|
I | 2.83 ± 0.05 | 1.05 ± 0.07 |
II | 2.86 ± 0.12 | 1.11 ± 0.15 |
III | 3.85 ± 0.19b+ | 2.28 ± 0.20c+ |
IV | 1.88 ± 0.39a− | 0.64 ± 0.33c− |
V | 3.10 ± 0.23a− | 1.51 ± 0.16a− |
VI | 2.56 ± 0.27b− | 1.30 ± 0.27b− |
VII | 2.62 ± 0.18b− | 0.98 ± 0.16c− |
b+ and c+ represent significant increases at p < 0.001 and p < 0.0001, respectively, when compared to Groups I and II values, respectively, while a-, b-, and c- represent significant decreases at p < 0.05, p < 0.001, and p < 0.0001, respectively, when compared to untreated positive control (DOX-only treated) (Group III) values, respectively.