Table 1.
Baseline characteristics according to absence and presence of AC in patients from MESA.
| AC, N = 3250 | No AC, N = 3405 | P value | |
|---|---|---|---|
| Demographics | |||
| Age (yr) | 66 ± 9 | 58 ± 9 | <0.01 |
| Gender, male (%) | 59 | 45 | 0.03 |
| Metabolic syndrome (%) | 40 | 38 | 0.04 |
| Hypertension (%) | 53 | 48 | 0.02 |
| Diabetes mellitus (%) | 34 | 28 | 0.02 |
| Body mass index (kg/m2) | 28 ± 5 | 28 ± 6 | 0.17 |
| SASP | |||
| IL-6 (mg/dL) | 1.6 ± 1 | 1.3 ± 1 | <0.01 |
| TNF-α (mg/dL) | 1469 ± 461 | 1294 ± 383 | <0.01 |
| Biochemical index | |||
| Total homocysteine (μmol/L) | 9.9 ± 3.6 | 8.5 ± 3.5 | <0.01 |
| Glucose (mmol/L) | 101 ± 33 | 99 ± 32 | 0.03 |
| Cholesterol (mmol/L) | 195 ± 35 | 193 ± 34 | 0.35 |
| Serum creatinine (μmol/L) | 1.0 ± 0.2 | 0.9 ± 0.5 | 0.04 |
| Vitamin K intake (μg) | 126.91 ± 130.55 | 135.86 ± 125.13 | <0.01 |
| Calcification score | |||
| Agatston score | 273 ± 53.2 | 0 | <0.01 |
Data are presented as mean ± SD. P values are from independent-sample t-test, Mann-Whitney U test, chi-squared test, and Fisher's exact test for appropriate data between group AC and group no AC.