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. 2020 Oct 31;20:13. doi: 10.1186/s12895-020-00105-y

Table 2.

Defined categories for prediction of defined disease severity by PDAI scores in total patients according to the anti-Dsg1 values (U/ml)

Patients Groups Anti-Dsg1 based categorization characteristics
Moderate Significant Extensive Sensitivity Specificity AUC
Total patients (n = 109) * Moderate-to-significant: <  128; Significant-to-extensive: > 128 0.49 0.91 0.71
Total patients (n = 109) ** < 179 179–182.5 > 182.5 0.33 1.00 0.68
0.63 0.89 0.74

Cut-off values are calculated based on *model-based clustering analysis and **25th and 75th percentiles

Abbreviations: PDAI pemphigus disease area index, anti-Dsg1 anti-desmoglein 1, AUC area under the curve