Table 2.
Baseline characteristics of the 4 experimental groups
| Parameter | Sham + Veh (n = 8) | Sham + TPPU (n = 9) | CA + Veh (n = 9) | CA + TPPU (n = 8) | p |
|---|---|---|---|---|---|
| Weight (kg) | 3.75 [3.54, 4.09] | 3.44 [3.26, 3.88] | 3.52 [3.44, 3.82] | 3.53 [3.24, 3.68] | 0.297 |
| ETCO2 (torr) | 46 [42, 49] | 47 [44, 54] | 48 [46, 50] | 44 [36, 48] | 0.293 |
| Temperature (°C) | 38.2 [38.0, 38.5] | 38.5 [37.9, 38.6] | 38.8 [38.1, 39.3] | 38.7 [37.8, 38.9] | 0.571 |
| MAP (mmHg) | 75 [64, 85] | 74 [71, 94] | 72 [68, 83] | 75 [70, 84] | 0.869 |
| HR (bpm) | 233 [187, 268] | 205 [190, 217] | 207 [185, 261] | 228 [216, 246] | 0.944 |
| Arterial pH | 7.41 [7.38, 7.45] | 7.36 [7.34, 7.38]a | 7.39 [7.37, 7.42] | 7.43 [7.41, 7.47] | 0.001 |
| PaCO2 (torr) | 33 [32, 36] | 36 [33, 39] | 38 [37, 39] | 35 [32, 37] | 0.104 |
| PaO2 (torr) | 169 [144, 172] | 159 [151, 167] | 161 [152, 171] | 153 [134, 217] | 0.987 |
| BE (mmol/L) | − 2.6 [− 4.7, 0.5] | − 5.1 [− 5.4, − 2.8] | − 1.7 [− 3.0, − 0.5] | 0.2 [− 3.3, 2.5] | 0.047 |
| Hb (g/dL) | 11.0 [10.6, 11.2] | 10.5 [9.3, 11.4] | 10.7 [10.1, 11.0] | 11.0 [10.8, 11.5] | 0.721 |
| Na (mmol/L) | 137 [134, 140] | 140 [135, 141] | 140 [138, 141] | 139 [135, 141] | 0.766 |
| Glu (mg/dL) | 103 [101, 123] | 142 [125, 166] | 160 [127, 199] | 121 [83, 135] | 0.077 |
All data are presented as median and interquartile range. Data were analyzed by Kruskal–Wallis test with post hoc Dunn’s multiple comparisons test
BE, base excess; bpm, beats per min; CA, cardiac arrest; ETCO2, end-tidal CO2; Glu, glucose; Hb, hemoglobin; HR, heart rate; MAP, mean arterial pressure; Na, sodium; PaCO2, arterial partial pressure of carbon dioxide; PaO2, arterial partial pressure of oxygen;Veh, vehicle
ap < 0.001 vs CA + TPPU